You can get these same strains in the dirt or on vegetables with dirt residue. They are microorganisms that are formed from spores. "Spore based" is just another way of saying "Soil based". Ulcerative colitis (UC) and Crohn's disease (CD) [inflammatory bowel disease (IBD) all have endotoxin in common (Caradonna, et al., 2000).Įndotoxin increases liver and organ damage from alcohol (Purohit, et al., 2008).Ĭirculating lipopolysaccharide significantly increased in chronically HIV-infected individuals (Brenchley, et al., 2006).Įndotoxin suppresses the thyroid gland, the immune system and leads to an increase in nitric oxide and the stress hormones estrogen, serotonin and prolactin, which further increase endotoxin production. The primary mechanism that we use to detoxify stored PUFAs from the liver is called glucuronidation, and this process is inhibited by endotoxin (Bánhegyi, et al, 1995). Glyphosate is just a small piece of the puzzle! Got stress? Restricting carbohydrates or animal protein? Low HCL? All of these factors ultimately affect endotoxin production and their effects on our bodies. Endotoxin itself increases intestinal permeability. When the system is compromised and cannot eliminate endotoxin, it passes through the intestinal wall, enters circulation and spreads throughout the entire system. You experiences allergies (food or environmental), autoimmune conditions, acne, eczema, rashes, constipation, diarrhea, acid reflux, infertility, menstrual dysfunction, irritable bowel disorder, diabetes, arthritis, migraines, edema, insomnia, poor sleep quality, energy dips, depression, anxiety, obsessive compulsive disorder, psychosis, the list goes on! This is where Mitolife’s endotoxin reducer comes in. In fact, endotoxins are commonly correlated with certain autoimmune conditions and skin issues. Likewise, not helping your gut biome by flushing it out every once in a while, can allow an increase of endotoxin to build up and instigate the immune system. Low stomach acid, hypothyroidism (carbohydrate or animal protein restriction), stress, intermittent fasting, ketogenic diets, and stress all create a build-up of endotoxin. Causing a host of other issues that can sometimes be mistaken for histamine intolerance, or mast cell activation syndrome. Under normal circumstances the liver and intestines can quickly eliminate it, but with polyunsaturated fat (PUFA) build-up in the liver and a lifetime of excessive fiber consumption, most people are compromised.įurther, these endotoxins essentially mimic low grade sepsis. These gram negative bacteria are part of our intestinal flora naturally. Endotoxin, or lipopolysaccharide, is a molecule that's bound to gram negative bacteria.
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